Eli Lilly (LLY) next-gen obesity drug achieves 28.3% weight loss

Published on 5/21/2026

Eli Lilly (LLY) next-gen obesity drug achieves 28.3% weight loss

AI Summary

Eli Lilly (LLY) announced that its next-generation obesity drug, retatrutide, successfully completed a late-stage trial, showing a significant weight loss of 28.3% on average over 80 weeks. Approximately 45% of 2,500 trial participants achieved 30% or more weight loss, and around 65% reached a BMI below 30. Analysts had anticipated retatrutide to outperform Lilly's current weight loss drug, Zepbound, which achieves about 20% to 22% weight loss. The expected sales for retatrutide could reach $3.8 billion by 2030, highlighting its potential impact in the growing weight loss and diabetes market, projected to value around $100 billion by that time.